THE UK BIOLOGICAL
Reconstruction and Regeneration, not Replacement
Thursday 30th &
Friday 31st January 2020
DOWNING COLLEGE, CAMBRIDGE
Academic Head of Dept Trauma & Orthopaedics University of Manchester, Honorary Consultant Orthopaedic Surgeon at Manchester University Foundation Trust, Honorary Professor at Salford University.
Leela trained in London, with fellowships in Sydney and London. She spent 8 years as T&O Surgeon in Edinburgh before moving to Manchester in 2016.
Her thesis was on Articular Cartilage Injuries in the Young Adult Knee. She was an ABC Fellow in 2010, and has won multiple awards for research. She has been peer-selected as one of the global top 15 cartilage repair surgeons to attend summits on advancing the science and surgery of cartilage repair, is an elected ICRS Senior Fellow, and founded the ICRS Global non-arthroplasty patient registry. Leela is a Lifetime Honorary Fellow of the Biological Knee Society in recognition of her work in this field.
Her clinical and research interests are in cartilage assessment and repair, biological regenerative surgery and arthroplasty. She currently serves as BASK Treasurer, ICRS Board and Chair of the Registry Committee, and on the British Orthopaedic Association Research Committee. She has published over 100 peer-reviewed scientific articles, and has authored many books including the latest edition of Grays Anatomy.
Biography coming soon.
Wasim Khan is a University Lecturer and Honorary Consultant Trauma and Orthopaedic Surgeon. He has a research interest in stem cell sources, characterisation, differentiation and clinical applications. His clinical interest is in Knee injuries and disease, especially cartilage and meniscal defects. He aims to identify better ways of treating cartilage and meniscal lesions in the knee and developing cell-based treatments.
Wasim was awarded a MRC Clinical Research Training Fellowship to complete his PhD looking at chondrogenesis in MSCs under the supervision of Professor Tim Hardingham at the University of Manchester. He was awarded the Syme Medal by the Royal College of Surgeons. Wasim then completed an Orthopaedic Academic Clinical Training programme at the Royal National Orthopaedic Hospital, Stanmore and University College London, where he was a Lecturer from 2010-14 under the supervision of Professor David Marsh and Professor Tim Briggs. Wasim has completed national (Bristol and Cardiff) and international (USA, Europe and Australia) clinical and research fellowships. He has authored over 300 papers, 50 chapters and 5 books.
Professor Stefan Lohmander, an Orthopaedic surgeon and researcher from Lund University in Sweden, was recently in Australia as part of a research network committed to improving the evidence-based treatment of patients with severe osteoarthritis. This network is a Centre for Research Excellence in Total Joint Replacement OPtimising oUtcomes, equity, cost effectiveness and patient Selection (OPUS), and involves researchers from 8 national and international universities as well as stakeholders from Government, health policy advice, guideline development, private health funding, consumer advocacy, registry and regulatory authority, training and hospital administration.
Professor McCaskie is an orthopaedic surgeon with an interest in lower limb surgery e.g. hip arthroscopy and related research. His research aims to develop innovative solutions, particularly regenerative, for patient benefit in musculoskeletal disease. One focus is Osteoarthritis (OA), which affects around 8 million people in the UK alone. The research encompasses a greater understanding of the causes of musculoskeletal disease and the mechanisms of action of therapy.
He is the Director of the Arthritis Research UK Tissue Engineering Centre. The £6 million Centre is based at four sites: Newcastle University, the University of Aberdeen, Keele University/the Robert Jones and Agnes Hunt Hospital NHS Foundation Trust in Oswestry and the University of York. Funded by a core grant of £2.4 million over five years from Arthritis Research UK with a further £3.4 million pledged by the four participating universities, the centre brings together leading clinicians, engineers and biologists from research and clinical groups. The aim and potential clinical impact is to treat early osteoarthritis by introducing stem cells into damaged joints in conjunction with existing surgical procedures. Prof McCaskie leads the Smart Step consortium (£1.1M) as part of Stage II UK Regenerative Medicine Platform. The aim is to develop cell-free approaches to Osteoarthritis and establish a translational pipeline for their development. He also facilitates Clinical Engagement as part of the Centre for Innovative Manufacturing in Medical Devices (MeDe) led by Leeds University.
Ian left the NHS in 2008 and he now works exclusively in the private sector. Ian is the co-founder and the Managing Partner of the London Sports Orthopaedics practice, based in the centre of The City of London.
Ian was the youngest ever surgeon to be elected as a Council Member and Trustee of the Royal College of Surgeons, and since 2005 he has been an Honorary Professor Associate in the School of Sport & Education at Brunel University.
Ian was the first surgeon in the UK to implant a Conformis G2 custom-made knee replacement, and he is now part of the Conformis Surgical Visitation Program, training other surgeons the techniques required for implanting Conformis prostheses. Ian was also the first knee surgeon in the UK to use Vivostat PRF biological glue, and he is now a designated ‘Centre of Excellence’ for Vivostat. In 2003 Ian was awarded the BASK President’s Medal for his research into meniscal repair, and in 2004 he was awarded an MS by Imperial College for his research into meniscal transplantation. Ian is now one of the UK’s leading experts in the field of meniscal transplantation, and he has been awarded ‘Centre of Excellence’ status by Hospital Innovations as a training centre for meniscal transplantation.
Ian specialises in complex knee reconstructions, and he is one of the founding members and the current President of the UK Biological Knee Society. Ian is also on the Editorial Board of The American Journal of Sports Medicine and also the Orthopaedics and Trauma journal, as well as being a reviewer for several other journals, including The Bone and Joint Journal, The Annals of the Royal College of Surgeons, The Journal of Biomechanics and The Clinical Journal of Sports Medicine.
Mr McDonnell is a University Lecturer and Honorary Consultant Knee and Hip Surgeon. His research interests are aimed at the identification and stratification of patients with early knee osteoarthritis, and defining their phenotypic features. He works closely with the department of radiology using novel imaging techniques. This is aimed at providing a personalised treatment aimed at the different phenotypes of early knee OA. He is the centre co ordinator for the ADIPOA2 clinical trial investigating the safety and efficacy of autologous adipose derived stem cells in the treatment of advanced OA of the knee. He undertook his previous research MD and orthopaedic surgical training in Oxford, based at the Nuffield Orthopaedic Centre. He undertook a specialist knee and hip “Sports and Joints” fellowship in Melbourne with the Melbourne Orthopaedic Group.
Honorary Professor Mike McNicholas is a Consultant Soft Tissue Knee and Trauma Surgeon at the University Hospital Aintree, Major Trauma Centre for the Cheshire and Mersey Region.
After completing Knee Fellowships in Edinburgh, Switzerland, America and Japan, he was appointed as a Consultant Trauma and Orthopaedic surgeon in Warrington General Hospital (2001), specialising in knee surgery. Mike qualified from the Universities of St Andrews (BSc, 1986), Manchester (MB, ChB, 1989) and Dundee (MD, 2000). His Orthopaedic training was in Dundee, and Edinburgh (FRCSEd Tr & Orth, 2000).
He is regularly invited to teach at national and international meetings, training juniors and other Consultants on arthroscopic surgery, osteotomy, ligament reconstruction, knee replacement and trauma surgery. He has been an Honorary Senior Lecturer Department of Musculoskeletal Biology at the Institute of Ageing and Chronic Disease, Faculty of Health & Life Sciences, University of Liverpool since August 2014 and has held an Honorary Professorship at the Directorate of Sport School of Health Care of the University of Salford since January 2006. He is an Associate Editor of the Journal of Orthopaedic Trauma and a reviewer for the Engineering and Physical Sciences Research Council, Medical Research Council, the Bone and Joint Journal and The British Medical Journal.
The Mersey Regional Training Rotation nominated him as Trainer of the Year in 2012. He is Faculty for Train the Trainer, Training Assessment in the Clinical Environment and Advanced Arthroscopy Courses of the Royal College of Surgeons.
Mike is also member of the National Ligament Registry and International Cartilage repair Society Steering Committees, promoting better outcomes data for anterior cruciate ligament reconstructions and articular cartilage regeneration techniques.
His current research interests include; stem cell applications in knee injury, outcomes following arthroplasty, ligament reconstruction, osteotomy, the treatment of focal articular cartilage defects and early arthritis using novel implants. Mike also focuses great interest on outcomes for complex trauma of the lower limb, such as high energy fractures treated by Ilizarov external fixation frames, multiligament injuries and dislocations of the knee and the surgical treatment of gunshot wounds.
Juliette Mellman-Jones is a practising solicitor and Medico-Legal Director of the Medical Professional Indemnity Group. She has defended healthcare practitioners for the entirety of her professional career. For 22 years, Juliette worked in a law firm, growing and developing a highly regarded team of lawyers. Juliette was Head of the Health and Care sector at BLM law firm in the City of London where she led the London healthcare team which was ranked as Band One within a leading legal directory. The same directory quoted clients describing Juliette as “great to deal with” and having a “very thorough understanding of new regulations.” Notable work includes representing one of the paediatric gastroenterologists in the longest-running GMC case ever to be heard which related to alleged serious professional misconduct arising out of the controversial research into the relationship between autism, inflammatory bowel disease and the MMR vaccine. Juliette’s client was the only one to be found not guilty of serious professional misconduct at the first hearing.
In November 2017, Juliette joined the MPI Group, a specialty specific medical indemnity organisation, as its Medico-Legal Director. The MPI Group supports a number of specialty specific indemnity schemes, including OTSIS (Orthopaedic and Trauma Specialists Indemnity Scheme), which offers high-quality, bespoke professional indemnity insurance for orthopaedic and trauma surgeons practising in the UK including an in-house medico-legal advisory service and access to an expert Clinical Board consisting of practising orthopaedic surgeons. Juliette heads up the medico-legal advisory service and leads the MPI Group.
Mr Joel Melton is a specialist knee surgeon treating all aspects of simple and complex knee problems. He consults at Cambridge University Hospitals NHS Trust and consults privately with admitting privileges at all local private hospitals. He enjoys the diagnostic process of identifying knee pathology and formulating effective treatment plans for patients and athletes, avoiding surgery whenever possible. Normal biomechanics of the knee joint are essential for proper function and the restoration of these biomechanics is crucial following injury. Mr Melton has a Masters degree in Orthopaedic Engineering and regularly applies his understanding of biomechanics to improve surgical outcomes.
His fellowship training at the world renowned North Sydney Orthopaedic and Sports Medicine Centre in Sydney, Australia provided wide-ranging experience of sports medicine and the management of knee injuries in elite athletes competing at national and international level. His current practice specialises in sports knee injuries and the reconstruction of cartilage and ligaments. Mr Melton performs as much of his surgery as possible using ‘keyhole’ techniques, avoiding the need for invasive procedures when possible. Further fellowships in France and Russia have equipped him with advanced techniques for the management of knee injuries and knee reconstruction.
At Cambridge University Hospitals, Mr Melton is part of a specialist department with many expert colleagues where he benefits from the opportunity to obtain and provide expert second opinions for complicated cases. In the NHS, he enjoys the opportunity of teaching and training junior surgeons, medical students and allied health professionals, holding the position of Associate Lecturer at Cambridge University. He is invited faculty on educational knee surgery courses and convenes several meetings and courses. He has delivered presentations and instructional course lectures both nationally and internationally and is widely published. He has active research interests in knee cartilage repair and ligament reconstruction, osteotomy and biomechanics.
Mr Melton has a passion for knee surgery and is dedicated to achieving the very best outcomes for his patients.
Mr James Murray started practicing as an orthopaedic consultant in Bristol in 2007. He holds elective NHS posts at The Avon Orthopaedic Centre where he is the clinical audit lead for orthopaedics, Southmead Hospital, and at Frenchay Hospital where he is also Trauma Director.
James graduated from Cambridge, underwent basic surgical training at Oxford before working in knee and hip research in Newcastle. He then entered orthopaedic specialist training in the Wessex Deanery and won the EndoPlus Knee Prize in 2005. In 2006, he spent a Fellowship year in Sydney, Australia at the internationally renowned Australian Institute of Musculoskeletal Surgery, gaining valuable experience in sports injuries and joint replacement surgery under the supervision of Merv Cross. That same year he was awarded the British Association of Surgery for the Knee travelling fellowship.
James has a keen research and training interest having written numerous published peer-reviewed papers and his first book, A to Z of Musculoskeletal and Trauma Radiology, which was published in June 2008. He also reviews for the journal, Clinical Orthopaedics and Related Research, and is a member of the Bristol Knee Group which carries out research and teaching related to knee surgery both in the UK and internationally.
His extensive experience has enabled him to offer a comprehensive knee service in both the public and private sectors. He is able to solve even the most complex of knee problems, reconstructing joints in patients with degenerative disease or those unfortunate enough to need a revision after their first or even second knee replacement. However, his main focus is on early post-operative mobility using techniques such as minimally-invasive muscle-sparing joint replacement and day-case ligament reconstruction.
Specialist in Orthopedics and Trauma Surgery in knee joint and cartilage surgery as well as ankle joint surgery
Rahul Patel is a Consultant in Trauma & Orthopaedics at the University College Hospital, London where he is also clinical lead for theatres and anaesthesia. He is actively involved in the training of higher surgical trainees on the London orthopaedic rotations and is also a co-developer and course tutor on the MSc in Sports Medicine, Exercise & Health at University College London. He is a senior honorary lecturer of University College London. In 2016 Rahul was the President of the Orthopaedics section at the Royal Society of Medicine.
Rahul Patel qualified from The Royal Free Hospital School of Medicine. He trained in surgery at various London teaching hospitals before undertaking a formal two-year research period culminating in a higher degree from the University of London. His specialist orthopaedic training was on the Middlesex/University College Hospital, London rotation. Rahul then undertook subspecialist fellowship training in reconstructive arthroscopy and sports orthopaedic surgery at the University of British Columbia, Vancouver, Canada and at the Steadman-Hawkins Clinic, Vail, USA.
Amongst others, he is a member of the British Association of Surgery of the Knee (BASK) Arthroscopy Association of North America (AANA), International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS), the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA) and the International Cartilage Repair Society (ICRS).
Mr Patel's main orthopaedic and research interests are sports injuries of the knee and hip, meniscal preservation and transplant, patellofemoral instability and multiligament injuries of the knee. He is passionate about digital healthcare and is the co-convenor of an annual meeting dedicated to this topic.
Yiannis trained at Dundee University and completed his Trauma & Orthopaedics training (CCT) through the Percivall Pott Orthopaedic Rotation based at St Bartholomew’s Hospital, London.
He undertook fellowships with Mr. Tim Spalding & Mr. A. Wilson. and was appointed as a Knee Consultant at the Royal Cornwall Hospital with a special interest in joint preservation surgery, primary joint arthroplasty and paediatric knee pathology.
His operation portfolio comprises of all trauma work with a focus on multi-ligament injuries and complex fractures around the knee. Electively he undertakes both arthroscopic and arthroplasty knee surgery.
Some of the procedures he offers include: meniscus repair/ augmentation/ transplantation, Cartilage biologic/ synthetic repair and resurfacing, ligament reconstruction/ repair/ augmentation, patellofemoral joint stabilisation, joint off-loading (Atlas Kinespring)/ knee osteotomy, compartmental arthroplasty and total knee replacement.
During my training he undertook and completed a Doctorate (M.D.) in Knee Pathology, titled Meniscectomy & Osteoarthritis, as well as a postgraduate Master of Philosophy (MPhil) degree in Medical Law & Ethics.
He maintains an active interest in research with ongoing national and international collaborations as well as teaching (academic tutor). Currently the Trust’s Consent and Knee Pathway Lead.
Having finished his trauma and orthopaedic training he undertook a fellowship in Lower Limb and Sports Injuries in Adelaide, South Australia. He has been a consultant in trauma and orthopaedics for 11 years with a specialist interest in the above. he provides orthopaedic services to a number of premiership and regional rugby clubs, particularly with knee injuries and have gained a lot of experience in the treatment of acute soft tissue sports injuries.
He is involved in a one in six on-call rota treating a broad spectrum of acute trauma and personal injury. On the elective orthopaedic side treats only limb orthopaedic conditions with specialist interest in knee surgery including ligament reconstruction, meniscal surgery including transplant, articular cartilage surgery, partial, bespoke and total knee replacement.
He has performed several hundred partial knee replacements and ACL reconstructions. and thousands of thousands of knee arthroscopies.
He has been clinical lead in his NHS department and supports the clinical director on a local trauma and orthopaedic board. He has also been audit lead for his department.
He is Honorary Clinical Tutor at Cardiff University, course governor for a number of courses at Welsh Institute for Minimal Access Therapy (WIMAT), and Honorary Surgeon to Pontypridd RFC and Crawshays RFC.
Prof. Seil studied medicine in Luxembourg and Brussels. He trained in Belgium and Germany (Dept. of Orthopaedic Surgery, University of Saarland Medical School, Homburg/Saar-Germany). Diploma of Orthopaedic Surgery in 1998 and of Special Orthopaedic Surgery in 2001 by the Medical Association of Saarland / Germany. He wrote his doctoral thesis on meniscal repair in 2001 and his professoral thesis (habilitation) on anterior cruciate ligament injuries in children in 2003. Prof. Seil works as an orthopaedic surgeon at the Centre Hospitalier de Luxembourg since September 2004 where he acted as Head of the Department of Orthopaedic and Trauma Surgery and, from 2008, as Head of the Department of the Locomotor system. His main areas of clinical activity are orthopaedic sports medicine as well as primary and revision knee reconstructive surgery. He was appointed extraordinary professor in orthopaedic surgery at the University of Saarland in 2007. Prof. Seil is co-director of the Luxembourg Olympic Medical Centre since 2008 and of the Sports Medicine Research Laboratory of the “Centre de Recherche Public – Santé” since 2009.
He was chairman of the arthroscopy committee of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS).
His scientific work deals with the analysis and improvement of diagnostic, surgical and non-surgical principles of overuse and sports-related joint injuries and diseases as well as on the investigation and promotion of primary and secondary prevention initiatives in sports medicine and joint surgery. Prof. Seil is editorial board member and reviewer of several scientific journals in orthopaedic surgery and sports medicine. He authored and co-authored numerous peer-reviewed publications and book chapters. Prof. Seil’s interest in knee osteotomies started in the late 1990’s where he collaborated closely with his colleague Prof. Dietrich Pape in the field, a collaboration which continues through the biannual organization of an international osteotomy course in Luxembourg.
In 2013 Jon was appointed Consultant Orthopaedic Knee Surgeon at The Mid Yorkshire Hospitals NHS Trust and Spire Healthcare. He currently carries out treatment at two hospitals: Spire Leeds Methley Park and Spire Elland Hospital in West Yorkshire.
Jon’s specialist interests include the management of sports injuries, partial knee replacement and joint preservation surgery in young adults. He is affiliated with a number of elite sports clubs in the Yorkshire region, including Super League and Championship rugby league teams.
His main interest outside surgery is sport, in particular, trail and fell running. He is a veteran of the iconic Yorkshire 3 Peaks Race, with a personal best of 3 hours 39 minutes and has recently completed the Ben Nevis Race in a sub 2-hour time. Jon has previously been a Yorkshire cross country champion and played senior level football in the West Riding County Amateur League. In the spring and summer months, Jon enjoys a leisurely game of golf with friends and colleagues.
Is a Consultant Orthopaedic Surgeon at The Royal Orthopaedic Hospital, specialising in arthroscopic Shoulder and Knee surgery. He graduated from Edinburgh University and undertook Registrar training in the Manchester region. After completion of training, he spent 18 months on fellowship in North America.12 months undertaking a Sports Medicine fellowship at the Sports Medicine Clinic of Nova Scotia and 6 months at the Holland Orthopaedic and Arthritic Centre in Toronto, gaining further experience in Shoulder and Knee surgery.
He is honorary Professor at Birmingham and Aston University where he supervises PhD students investigating the use of stem cells in cartilage repair, tendon regeneration and rehabilitation following injury. Prof Snow has written over 50 publications in various International medical journals and 4 book chapters on knee and shoulder injuries.
Peter Thompson is a consultant specialist knee and trauma surgeon at the University Hospitals of Coventry and Warwickshire.
He qualified from Birmingham University Medical School in 1992 and completed specialist training in orthopaedic and trauma surgery in London in 2004 before undertaking a fellowship in Knee, Sports and Arthroplasty Surgery in Victoria, Australia. His interests cover a full range of knee problems from sports injuries to the treatment of the arthritic knee.
He is committed to training junior surgeons at UHCW, teaching various aspects of knee surgery at both national and international meetings as well as lecturing at Warwick University.